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Piracetam (trade names include Nootropil, Breinox; Cebrotonin; Ciclofalina; Gabacet; Geratam; Knowful; Latropil; Lucetam; Mersitropil; Piracetam Neuraxpharm; Neurocetam; Normabrain; Pirabene; Piracetam Ratiopharm; Revolan) is a nootropic medication. This medicine is indicated for the treatment of various cognitive disorders, including post-stroke aphasia, cognitive decline following heart and brain surgery, dementia, Alzheimer's disease, myoclonus, epilepsy, depression, anxiety, mood changes, behavioral disorders, vertigo, dyslexia, sickle cell anemia, mental retardation in children; to reduce the duration of vestibular nystagmus; to control twitching and jerking of the muscles; for combined therapy in patients with poor tolerance to antipsychotics. Piracetam is also widely used off-label as memory enhancer, cognitive enhancer (cognitive booster) to improve cognition and concentration, as an athletic performance, and other conditions. It has a positive effect on metabolism and blood circulation of the brain. Nootropil increases glucose utilization, improves the course of metabolic processes, improves microcirculation in the ischemic areas, and inhibits the aggregation of activated platelets. This drug has a protective effect for brain damage caused by hypoxia, intoxication, an electric shock. Piracetam improves the integrative activity of the brain. This medication does not have a sedative and excessive stimulating effect.
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General information about Piracetam (Nootropil):
Medical and pharmaceutical categories for piracetam:
Anti anxiety drugs
Derivatives of GABA
Nootropics and neurotonics
The Anatomical Therapeutic Chemical (ATC) classification system piracetam codes:
N - Nervous system
N06 - Psychoanaleptics
N06B - Psychostimulants, agents used for adhd and nootropics
N06BX - Other psychostimulants and nootropics
N06BX03 - Piracetam
Piracetam in The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:
Sickle-cell disorders - D57
Dementia in Alzheimer's disease ( G30.-+ ) - F00*
Vascular dementia - F01
Unspecified dementia - F03
Personality and behavioural disorders due to brain disease, damage and dysfunction - F07
Mental and behavioural disorders due to use of alcohol - F10
Mood [affective] disorders - F30-F39
Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders - F40-F48
Reaction to severe stress, and adjustment disorders - F43
Unspecified mental retardation - F79
Specific developmental disorders of speech and language - F80
Secondary parkinsonism - G21
Other extrapyramidal and movement disorders - G25
Myoclonus - G25.3
Alzheimer's disease - G30
Epilepsy and recurrent seizures - G40
Migraine - G43
Other disorders of brain - G93
Nystagmus and other irregular eye movements - H55
Disorders of vestibular function - H81
Other disorders of ear, not elsewhere classified - H93
Intracerebral haemorrhage - I61
Cerebral infarction - I63
Other cerebrovascular diseases - I67
Sequelae of cerebrovascular disease - I69
Dizziness and giddiness - R42
Speech disturbances, not elsewhere classified - R47
Aphasia - R47.01
Dyslexia and other symbolic dysfunctions, not elsewhere classified - R48
Intracranial injury - S06
Sequelae of injuries of head - T90
Pregnancy and breastfeeding categories for Piracetam (Nootropil):
The safety of Piracetam (Nootropil) for use during pregnancy has not been established. For this reason, this medicine should not be used in pregnancy unless considered essential by your doctor, and only if the benefit of its use outweighs the risk to the unborn child. Women who could get pregnant should use a reliable method of contraception to avoid getting pregnant while taking this medicine. Seek further medical advice from your doctor.
Piracetam passes into breast milk. This medication should not be used by breastfeeding mothers. Mothers who need treatment with this medicine should not breastfeed and bottlefeed instead. Discuss this with your doctor.
Salts and other piracetam forms used as active pharmaceutical ingredients (API):
Synonyms of piracetam, international and chemical names:
Best known piracetam brands, generics and trade names in various countries:
Benocetam - Bernofarm
Breinox - Novapharma
Bretam - Korea United Pharmaceutical
Ceact - Crescent Therapeutics
Cebrotonin - Walter Ritter; IDS Group; JDH Pharmaceutical
Ciclofalina - Almirall
Cintilan - Medley Industria Farmaceutica
Fepinram - Dexa Medica Pharm & Chem; DKSH
Gabacet - Sanofi-Aventis
Geratam - UCB Pharma
Knowful - Y.S.P. Industries; Y.K. Pharma
Latropil - Lapi
Lucetam - Egis
Memotropil - Polpharma; VP Pharma Baru
Mempil - General Drugs House
Mersitropil - Mersifarma Tirmaku Mercusana
Neurocet - Hexpharm Jaya Laboratories
Neurocetam - Micro Labs; Brown & Burk Pharmaceuticals
Neurofit - Shine Pharmaceuticals
Neurotam - Kalbe Farma
Noostan - UCB Pharma; Rontag Laboratorios
Nootron - Biosintetica Laboratorios
Nootrop - UCB Pharma
Nootropil - UCB Pharma; GlaxoSmithKline; Grunenthal; Pliva; Sanofi-Aventis
Nootropyl - UCB Pharma; Sanofi-Aventis
Normabrain - UCB Pharma; Torrent Pharmaceuticals
Nurocer - InnoGen Pharma Group
Oikamid - Pliva
Pirabene - Ratiopharm
Piracebral - Hexal
Piracetam - Arrow Generiques; Biogaran; CT-Arzneimittel; EG Labo; Egis; Gedeon Richter; Merck; Mylan; Neuraxpharm Arzneimittel; Ranbaxy; Ratiopharm; Sandoz; Stada; Teva
Pratropil - Fahrenheit
Psycoton - Benedetti
Racetam - Samjin Pharmaceutical; Zyfas Medical
Retento - XL Laboratories
Revolan - Sanbe Farma
Syntam - Synmosa Biopharma Corporation; Zyfas Medical
Pharmaceutical active ingredients used in medicine in combinations with piracetam:
Some other medications in Nootropil (Piracetam) pharmacological classes:
PIRACETAM (NOOTROPIL) MEDICATION GUIDE
How does Piracetam / Generic Nootropil work?
Piracetam does not have agonistic or inhibitory effect on synaptic junction like other neurotransmitters. Nootropil influences cognitive function without acting as a sedative or a stimulant. This medication acts on ion channels (Na+, K+) or ion carriers leading to non-specific increased neuron excitability. Piracetam increases blood flow and oxygen consumption in parts of the brain by increasing ATP metabolism. Nootropil improves the function of the neurotransmitter acetylcholine through muscarinic cholinergic (ACh) receptors, which are implicated in memory processes. This medicine also acts on NMDA glutamate receptors, which is involved in learning and memory processes. Piracetam increases cell membrane permeability.
Why is Piracetam (Nootropil) prescribed?
dementia due to cerebrovascular events (ischemic stroke)
in old age
comatose state of vascular
traumatic or toxic origin
treatment withdrawal and psychoorganic syndrome in chronic alcoholism
learning disorders in children not related to inadequate training or the peculiarities of family environment (as part of combination therapy)
sickle cell anemia (as part of combination therapy).
Side effects of Piracetam
The common side effects reported with piracetam are anxiety, insomnia, irritability, headache, agitation, nervousness, tremor, anxiety, trembling, fatigue, drowsiness, occasional dryness of the mouth, increased libido, weight gain and hypersensitive skin reactions.
Guidelines before using Piracetam (Nootropil) generic
This medication should not be administered in patients with severe renal impairment. The concomitant use of piracetam and thyroid hormone extracts produce confusion, irritability and sleeping disorders. It is not advisable to consume the Nootropil during pregnancy. If it is an absolute must to take piracetam during pregnancy, it should be administered under the supervision of a medical practitioner. This drug is not recommended for use by nursing mothers.
What are the common dosages of this medication?
The recommended starting dosage of piracetam is 800 mg to 1 g three times daily. The dose of Nootropil in children is 20 mg / kg twice or thrice daily.
What is the difference between brand and generic Piracetam (Nootropil)?
The active ingredient is piracetam in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can buy cheap Nootropil medicine when it is sold as a generic variant.
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